You pour your heart and soul into a story. You spend hours upon days upon weeks upon months writing this book. You think about it when you're going to bed and it's one of the first things you think about waking up. Plot lines come to you in the middle of the night, character details are fleshed out in the shower.
The book is your baby.
So, you take a deep breath and take it to a conference. You meet an agent who amazingly enough wants to represent you. And then he/she begins to send it to publishers.
And then they come.
By the singles, then the doubles, then sometimes by the dozens.
If you are really wanting to pursue writing, you're going to HAVE to develop a thick skin. People are going to say mean things about your work - whether it's an editor turning down your book or a reader who didn't like it - you will never make everyone a fan of your writing.
Sometimes, I have to make myself not look on Amazon because I can really get into a mini-depression when I read some of the reviews on my books. I start thinking that no one likes them, why should I bother, it's not worth it, etc., etc. It's so easy to fly right past the great reviews to the ones that are awful.
Not everyone is going to like what you have to say. Not everyone is going to read your book and laugh or smile or feel like they know God better.
But one person might.
Maybe that one person will even come to know Him for the first time.
Would that make it worth the heartache? Worth the sinking feeling deep in your stomach when someone harshly criticizes something you poured yourself into?
So keep at it! Write what you feel the need to write. When all is said and done, the only review that matters is the one that God gives. And if you're writing to glorify Him, then I guarantee that you'll get five stars. :)